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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larB1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)    
Predicted Functional Partners:
KZE54708.1
ATP-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
KZE54030.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
KZE54028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.806
fnr
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.753
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.
    
  0.637
purM
Phosphoribosylaminoimidazole synthetase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.593
zapA
Z ring-associated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
       0.574
KZE48389.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.569
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.537
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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