| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KZE49487.1 | KZE51914.1 | AV540_15315 | AV540_11560 | NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.994 |
| KZE49487.1 | lgrD | AV540_15315 | AV540_01950 | NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-ribosomal peptide synthetase; Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes the NAD(P)H-dependent reduction of the C-terminal glycine residue of the N- formylated 16-mer peptide, that binds to the peptidyl carrier domain of the terminal module of this protein, to form a peptidyl-aldehyde intermediate that is released from the enzyme complex. | 0.982 |
| KZE49487.1 | rnhB | AV540_15315 | AV540_08845 | NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.823 |
| KZE51719.1 | dnaN | AV540_12700 | AV540_04280 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.508 |
| KZE51719.1 | rnhB | AV540_12700 | AV540_08845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.832 |
| KZE51719.1 | thyA | AV540_12700 | AV540_10385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.650 |
| KZE51914.1 | KZE49487.1 | AV540_11560 | AV540_15315 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
| KZE51914.1 | dnaN | AV540_11560 | AV540_04280 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.496 |
| KZE51914.1 | lgrD | AV540_11560 | AV540_01950 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Non-ribosomal peptide synthetase; Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes the NAD(P)H-dependent reduction of the C-terminal glycine residue of the N- formylated 16-mer peptide, that binds to the peptidyl carrier domain of the terminal module of this protein, to form a peptidyl-aldehyde intermediate that is released from the enzyme complex. | 0.999 |
| KZE51914.1 | rbgA | AV540_11560 | AV540_08850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Ribosome biogenesis GTPase YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.721 |
| KZE51914.1 | rnhB | AV540_11560 | AV540_08845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.901 |
| KZE53150.1 | rbgA | AV540_08835 | AV540_08850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome biogenesis GTPase YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.609 |
| KZE53150.1 | rnhB | AV540_08835 | AV540_08845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.878 |
| KZE53150.1 | sipS | AV540_08835 | AV540_08855 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.559 |
| dnaN | KZE51719.1 | AV540_04280 | AV540_12700 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.508 |
| dnaN | KZE51914.1 | AV540_04280 | AV540_11560 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.496 |
| dnaN | rnhA | AV540_04280 | AV540_18410 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.508 |
| dnaN | rnhB | AV540_04280 | AV540_08845 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.953 |
| dnaN | thyA | AV540_04280 | AV540_10385 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.888 |
| lgrD | KZE49487.1 | AV540_01950 | AV540_15315 | Non-ribosomal peptide synthetase; Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes the NAD(P)H-dependent reduction of the C-terminal glycine residue of the N- formylated 16-mer peptide, that binds to the peptidyl carrier domain of the terminal module of this protein, to form a peptidyl-aldehyde intermediate that is released from the enzyme complex. | NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
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