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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZE52794.1Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (467 aa)    
Predicted Functional Partners:
KZE44081.1
Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
0.732
KZE52793.1
NAD(P)H dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.677
KZE54643.1
Peptidase M6; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.663
AV540_01910
Type IV secretion protein Rhs; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.639
KZE40892.1
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.636
KZE52825.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.636
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.589
KZE39230.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.586
yvgT
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
KZE48825.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.544
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.