| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KZE39406.1 | KZE51719.1 | AV540_03415 | AV540_12700 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.625 |
| KZE39406.1 | thyA | AV540_03415 | AV540_10385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.788 |
| KZE42002.1 | KZE51719.1 | AV540_03010 | AV540_12700 | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.642 |
| KZE42002.1 | ndk | AV540_03010 | AV540_05285 | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.558 |
| KZE42002.1 | polA | AV540_03010 | AV540_16260 | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.593 |
| KZE51719.1 | KZE39406.1 | AV540_12700 | AV540_03415 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.625 |
| KZE51719.1 | KZE42002.1 | AV540_12700 | AV540_03010 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | 0.642 |
| KZE51719.1 | flgC | AV540_12700 | AV540_08715 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Flagellar basal-body rod protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family. | 0.703 |
| KZE51719.1 | ndk | AV540_12700 | AV540_05285 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.618 |
| KZE51719.1 | polA | AV540_12700 | AV540_16260 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.889 |
| KZE51719.1 | rnhB | AV540_12700 | AV540_08845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.832 |
| KZE51719.1 | ssb | AV540_12700 | AV540_04145 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.843 |
| KZE51719.1 | thyA | AV540_12700 | AV540_10385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.650 |
| KZE51719.1 | topA | AV540_12700 | AV540_08750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.817 |
| KZE51719.1 | topB_1 | AV540_12700 | AV540_23750 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.817 |
| flgC | KZE51719.1 | AV540_08715 | AV540_12700 | Flagellar basal-body rod protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| ndk | KZE42002.1 | AV540_05285 | AV540_03010 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | 0.558 |
| ndk | KZE51719.1 | AV540_05285 | AV540_12700 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.618 |
| ndk | ssb | AV540_05285 | AV540_04145 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.516 |
| polA | KZE42002.1 | AV540_16260 | AV540_03010 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | 0.593 |