close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZE48983.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)    
Predicted Functional Partners:
sigW_2
RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.934
yshE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
KZE48984.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
KZE53114.1
Flagellar basal body protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
     0.726
cdaA
Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.725
KZE53110.1
Flagellar biosynthesis protein FliZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.697
KZE52277.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.670
KZE50018.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.664
ywgA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.637
KZE50074.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.634
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.