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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZE49019.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)    
Predicted Functional Partners:
ytbE
Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.835
KZE44588.1
Aquaporin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.761
KZE52395.1
Glyoxal reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.722
KZE48389.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.713
ytcD
HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.620
KZE51914.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.574
KZE49018.1
Arabinose transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.527
KZE46262.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.512
KZE44092.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
   0.483
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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