Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fxsAExclusion suppressor FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)    
Predicted Functional Partners:
KZE48797.1
Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.870
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.808
KZE46395.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.637
KZE55554.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.637
ytcJ
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.637
KZE46507.1
Heat-shock protein Hsp20; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family.
   
    0.620
clpY
Clp protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
  
 0.619
KZE48796.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
KZE48795.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.522
pyk
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.504
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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