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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbUPhosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)    
Predicted Functional Partners:
rsbW
Anti-sigma B factor RsbW; Binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
rsbT
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
KZE46822.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.973
KZE46821.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.972
KZE39230.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.953
sigB
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.945
rsbV
Anti-sigma B factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   
 0.909
KZE50359.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.853
KZE44677.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.843
KZE39292.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.838
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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