| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KZE43843.1 | KZE44126.1 | AV540_24735 | AV540_02165 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| KZE43843.1 | KZE46852.1 | AV540_24735 | AV540_21310 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |
| KZE43843.1 | glyA | AV540_24735 | AV540_13080 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.807 |
| KZE43843.1 | glyA_2 | AV540_24735 | AV540_15180 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.856 |
| KZE43843.1 | ilvA | AV540_24735 | AV540_14120 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.863 |
| KZE43843.1 | ilvH | AV540_24735 | AV540_13765 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.549 |
| KZE43843.1 | sdaAA | AV540_24735 | AV540_19610 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.935 |
| KZE43843.1 | sdaAB | AV540_24735 | AV540_19615 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.935 |
| KZE43843.1 | thrB | AV540_24735 | AV540_21320 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.882 |
| KZE43843.1 | trpA | AV540_24735 | AV540_05335 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.868 |
| KZE44126.1 | KZE43843.1 | AV540_02165 | AV540_24735 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| KZE44126.1 | KZE46852.1 | AV540_02165 | AV540_21310 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.839 |
| KZE44126.1 | glyA | AV540_02165 | AV540_13080 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.856 |
| KZE44126.1 | glyA_2 | AV540_02165 | AV540_15180 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.958 |
| KZE44126.1 | ilvA | AV540_02165 | AV540_14120 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.942 |
| KZE44126.1 | ilvH | AV540_02165 | AV540_13765 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| KZE44126.1 | sdaAA | AV540_02165 | AV540_19610 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.944 |
| KZE44126.1 | sdaAB | AV540_02165 | AV540_19615 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.962 |
| KZE44126.1 | thrB | AV540_02165 | AV540_21320 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.855 |
| KZE44126.1 | trpA | AV540_02165 | AV540_05335 | Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.931 |