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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZE45027.1Xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
degS
Histidine kinase; Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.
       0.773
KZE49365.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.728
KZE45042.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.712
degU
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
KZE52776.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.595
KZE52339.1
Hyaluronan synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.587
KZE48766.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.518
KZE49511.1
Sugar-binding domain protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.500
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.491
KZE54621.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.487
Your Current Organism:
Brevibacillus parabrevis
NCBI taxonomy Id: 54914
Other names: ATCC 10027, B. parabrevis, Bacillus parabrevis, CIP 103840, DSM 8376, IFO 12334, JCM 8506, LMG 15971, LMG:15971, NBRC 12334, NCIMB 13346, NRRL NRS-605, NRRL NRS-815
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