Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (505 aa)    
Predicted Functional Partners:
KNB73258.1
precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KNB73255.1
cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
KNB73262.1
Cobalt-precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.997
KNB73261.1
Precorrin-2 C20-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
  
 0.996
KNB73250.1
Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.993
KNB73257.1
Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.993
KNB73260.1
Cobalamin biosynthesis protein CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.993
Your Current Organism:
Brevibacillus reuszeri
NCBI taxonomy Id: 54915
Other names: ATCC 51665, B. reuszeri, Bacillus reuszeri, CIP 104543, DSM 9887, IFO 15719, JCM 9170, LMG 16012, LMG:16012, NBRC 15719, strain H.W. Reuszer Army strain 39
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