STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNB71267.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)    
Predicted Functional Partners:
codY-2
GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
     0.609
KNB72769.1
50S ribosomal protein L7ae; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.588
KNB71268.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
       0.569
codY
Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
     0.566
KNB72597.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
KNB71271.1
Cation transporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
       0.467
KNB72688.1
Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
 
     0.454
KNB72596.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.437
KNB74102.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.418
KNB74701.1
Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.409
Your Current Organism:
Brevibacillus reuszeri
NCBI taxonomy Id: 54915
Other names: ATCC 51665, B. reuszeri, Bacillus reuszeri, CIP 104543, DSM 9887, IFO 15719, JCM 9170, LMG 16012, LMG:16012, NBRC 15719, strain H.W. Reuszer Army strain 39
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.