acsA-2 protein (Microvirga guangxiensis) - STRING interaction network

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acsA-2

Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa)

Predicted Functional Partners:

SCY71257.1

0.882

SCY32954.1

0.864

SCZ05021.1

0.864

SCY94458.1

0.814

SCZ02510.1

0.802

SCX84952.1

0.799

SCZ09911.1

0.799

glcB

0.791

SCY82848.1

0.756

SCZ04448.1

0.732

Your Current Organism:

Microvirga guangxiensis

NCBI taxonomy Id: 549386
Other names: CGMCC 1.7666, JCM 15710, M. guangxiensis, Microvirga guangxiensis Zhang et al. 2009, Microvirga sp. 25B, strain 25B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCX84952.1	SCY32954.1	SAMN02927923_00118	SAMN02927923_01180	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	3-hydroxyacyl-CoA dehydrogenase.	0.841
SCX84952.1	SCY71257.1	SAMN02927923_00118	SAMN02927923_02090	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	3-hydroxyacyl-CoA dehydrogenase.	0.841
SCX84952.1	SCY82848.1	SAMN02927923_00118	SAMN02927923_02487	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.974
SCX84952.1	SCZ02510.1	SAMN02927923_00118	SAMN02927923_03490	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Indolepyruvate ferredoxin oxidoreductase.	0.861
SCX84952.1	SCZ04448.1	SAMN02927923_00118	SAMN02927923_03618	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Acetyltransferase.	0.846
SCX84952.1	SCZ05021.1	SAMN02927923_00118	SAMN02927923_03676	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.	0.841
SCX84952.1	SCZ09911.1	SAMN02927923_00118	SAMN02927923_04091	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Allosteric NADP-dependent malic enzyme.	0.831
SCX84952.1	acsA-2	SAMN02927923_00118	SAMN02927923_02027	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.799
SCX84952.1	glcB	SAMN02927923_00118	SAMN02927923_04120	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.939
SCY32954.1	SCX84952.1	SAMN02927923_01180	SAMN02927923_00118	3-hydroxyacyl-CoA dehydrogenase.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.841
SCY32954.1	SCY71257.1	SAMN02927923_01180	SAMN02927923_02090	3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase.	0.791
SCY32954.1	SCY82848.1	SAMN02927923_01180	SAMN02927923_02487	3-hydroxyacyl-CoA dehydrogenase.	Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.855
SCY32954.1	SCY94458.1	SAMN02927923_01180	SAMN02927923_02998	3-hydroxyacyl-CoA dehydrogenase.	anthraniloyl-CoA monooxygenase.	0.623
SCY32954.1	SCZ02510.1	SAMN02927923_01180	SAMN02927923_03490	3-hydroxyacyl-CoA dehydrogenase.	Indolepyruvate ferredoxin oxidoreductase.	0.831
SCY32954.1	SCZ04448.1	SAMN02927923_01180	SAMN02927923_03618	3-hydroxyacyl-CoA dehydrogenase.	Acetyltransferase.	0.738
SCY32954.1	SCZ05021.1	SAMN02927923_01180	SAMN02927923_03676	3-hydroxyacyl-CoA dehydrogenase.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.	0.838
SCY32954.1	SCZ09911.1	SAMN02927923_01180	SAMN02927923_04091	3-hydroxyacyl-CoA dehydrogenase.	Allosteric NADP-dependent malic enzyme.	0.841
SCY32954.1	acsA-2	SAMN02927923_01180	SAMN02927923_02027	3-hydroxyacyl-CoA dehydrogenase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.864
SCY32954.1	glcB	SAMN02927923_01180	SAMN02927923_04120	3-hydroxyacyl-CoA dehydrogenase.	Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.	0.718
SCY71257.1	SCX84952.1	SAMN02927923_02090	SAMN02927923_00118	3-hydroxyacyl-CoA dehydrogenase.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.841

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