node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCX81086.1 | SCY33332.1 | SAMN02927923_00017 | SAMN02927923_01191 | 3-isopropylmalate dehydrogenase. | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | 0.676 |
SCX81086.1 | SCY54867.1 | SAMN02927923_00017 | SAMN02927923_01634 | 3-isopropylmalate dehydrogenase. | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 0.694 |
SCX81086.1 | SCY70071.1 | SAMN02927923_00017 | SAMN02927923_02032 | 3-isopropylmalate dehydrogenase. | Acetolactate synthase, large subunit. | 0.805 |
SCX81086.1 | SCY70127.1 | SAMN02927923_00017 | SAMN02927923_02034 | 3-isopropylmalate dehydrogenase. | Acetolactate synthase, small subunit. | 0.944 |
SCX81086.1 | SCY80309.1 | SAMN02927923_00017 | SAMN02927923_02351 | 3-isopropylmalate dehydrogenase. | Homoserine dehydrogenase. | 0.413 |
SCX81086.1 | SCY84666.1 | SAMN02927923_00017 | SAMN02927923_02574 | 3-isopropylmalate dehydrogenase. | Threonine dehydratase. | 0.484 |
SCX81086.1 | SCZ05806.1 | SAMN02927923_00017 | SAMN02927923_03738 | 3-isopropylmalate dehydrogenase. | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 0.673 |
SCX81086.1 | ilvC | SAMN02927923_00017 | SAMN02927923_02036 | 3-isopropylmalate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.904 |
SCX81086.1 | leuA | SAMN02927923_00017 | SAMN02927923_02045 | 3-isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.912 |
SCX81086.1 | leuB | SAMN02927923_00017 | SAMN02927923_00764 | 3-isopropylmalate dehydrogenase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.724 |
SCY33332.1 | SCX81086.1 | SAMN02927923_01191 | SAMN02927923_00017 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase. | 0.676 |
SCY33332.1 | SCY70127.1 | SAMN02927923_01191 | SAMN02927923_02034 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.995 |
SCY33332.1 | SCY80309.1 | SAMN02927923_01191 | SAMN02927923_02351 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | Homoserine dehydrogenase. | 0.469 |
SCY33332.1 | ilvC | SAMN02927923_01191 | SAMN02927923_02036 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.939 |
SCY33332.1 | leuA | SAMN02927923_01191 | SAMN02927923_02045 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.784 |
SCY33332.1 | leuB | SAMN02927923_01191 | SAMN02927923_00764 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.769 |
SCY54867.1 | SCX81086.1 | SAMN02927923_01634 | SAMN02927923_00017 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase. | 0.694 |
SCY54867.1 | SCY70071.1 | SAMN02927923_01634 | SAMN02927923_02032 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit. | 0.599 |
SCY54867.1 | SCY70127.1 | SAMN02927923_01634 | SAMN02927923_02034 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.992 |
SCY54867.1 | SCY84666.1 | SAMN02927923_01634 | SAMN02927923_02574 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.700 |