node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OKH45208.1 | OKH49930.1 | NIES30_20250 | NIES30_04255 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.508 |
OKH45208.1 | ilvC | NIES30_20250 | NIES30_16170 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.431 |
OKH45208.1 | nadD | NIES30_20250 | NIES30_16030 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.439 |
OKH45208.1 | nadE | NIES30_20250 | NIES30_16045 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.859 |
OKH45208.1 | pntB | NIES30_20250 | NIES30_04260 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.502 |
OKH45208.1 | ppnK | NIES30_20250 | NIES30_00505 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.538 |
OKH45208.1 | ppnK-2 | NIES30_20250 | NIES30_06875 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.538 |
OKH45208.1 | rpoC1 | NIES30_20250 | NIES30_07445 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit gamma; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.424 |
OKH45208.1 | rpoC2 | NIES30_20250 | NIES30_07440 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. | 0.424 |
OKH49930.1 | OKH45208.1 | NIES30_04255 | NIES30_20250 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.508 |
OKH49930.1 | OKH49980.1 | NIES30_04255 | NIES30_04530 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. | 0.693 |
OKH49930.1 | ilvC | NIES30_04255 | NIES30_16170 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.506 |
OKH49930.1 | nadD | NIES30_04255 | NIES30_16030 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.630 |
OKH49930.1 | nadE | NIES30_04255 | NIES30_16045 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.823 |
OKH49930.1 | pntB | NIES30_04255 | NIES30_04260 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
OKH49930.1 | ppnK | NIES30_04255 | NIES30_00505 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.654 |
OKH49930.1 | ppnK-2 | NIES30_04255 | NIES30_06875 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.654 |
OKH49930.1 | rpoC1 | NIES30_04255 | NIES30_07445 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit gamma; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.528 |
OKH49930.1 | rpoC2 | NIES30_04255 | NIES30_07440 | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. | 0.528 |
OKH49980.1 | OKH49930.1 | NIES30_04530 | NIES30_04255 | Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. | NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |