STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT66085.1Hpr(Ser) kinase/phosphatase; Belongs to the HPrK/P family. (310 aa)    
Predicted Functional Partners:
SIT91268.1
Catabolite repression HPr-like protein.
 
 
 
 0.748
SIT67595.1
Serine/threonine protein kinase.
   
 
 0.670
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
     0.529
SIT69213.1
Glucosamine-6-phosphate deaminase.
  
  
 0.500
SIT66091.1
Hypothetical protein.
       0.495
SIT66073.1
Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family.
  
    0.463
SIT87903.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.462
SIT66079.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).
       0.459
lgt
Phosphatidylglycerol:prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.459
SIT74491.1
ROK family protein (putative glucokinase).
   
 
 0.424
Your Current Organism:
Edaphobacillus lindanitolerans
NCBI taxonomy Id: 550447
Other names: Bacillus sp. MNA4, CCM 7584, DSM 22424, E. lindanitolerans, strain MNA4
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