node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIT67242.1 | SIT67628.1 | SAMN05428946_0184 | SAMN05428946_0248 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.449 |
SIT67242.1 | birA | SAMN05428946_0184 | SAMN05428946_0059 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.456 |
SIT67242.1 | coaD | SAMN05428946_0184 | SAMN05428946_0301 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.639 |
SIT67242.1 | coaE | SAMN05428946_0184 | SAMN05428946_1769 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.435 |
SIT67242.1 | guaA | SAMN05428946_0184 | SAMN05428946_2863 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.450 |
SIT67628.1 | SIT67242.1 | SAMN05428946_0248 | SAMN05428946_0184 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.449 |
SIT67628.1 | birA | SAMN05428946_0248 | SAMN05428946_0059 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.761 |
SIT67628.1 | coaD | SAMN05428946_0248 | SAMN05428946_0301 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.687 |
SIT67628.1 | coaE | SAMN05428946_0248 | SAMN05428946_1769 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.763 |
SIT67628.1 | coaX | SAMN05428946_0248 | SAMN05428946_2995 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.765 |
SIT67954.1 | SIT82556.1 | SAMN05428946_0299 | SAMN05428946_1522 | PDZ domain-containing protein. | Competence protein ComEA. | 0.616 |
SIT67954.1 | coaD | SAMN05428946_0299 | SAMN05428946_0301 | PDZ domain-containing protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.701 |
SIT67977.1 | coaD | SAMN05428946_0302 | SAMN05428946_0301 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.984 |
SIT82556.1 | SIT67954.1 | SAMN05428946_1522 | SAMN05428946_0299 | Competence protein ComEA. | PDZ domain-containing protein. | 0.616 |
SIT82556.1 | coaD | SAMN05428946_1522 | SAMN05428946_0301 | Competence protein ComEA. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.662 |
SIT82556.1 | nadD | SAMN05428946_1522 | SAMN05428946_1526 | Competence protein ComEA. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.568 |
birA | SIT67242.1 | SAMN05428946_0059 | SAMN05428946_0184 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.456 |
birA | SIT67628.1 | SAMN05428946_0059 | SAMN05428946_0248 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.761 |
birA | coaD | SAMN05428946_0059 | SAMN05428946_0301 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.736 |
birA | coaX | SAMN05428946_0059 | SAMN05428946_2995 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.847 |