STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT82624.1Hypothetical protein. (173 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.961
SIT82615.1
Hypothetical protein.
 
  
 0.875
SIT82578.1
Putative HD superfamily hydrolase of NAD metabolism.
 
    0.867
SIT82597.1
RNA-binding protein.
  
    0.832
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.816
rsfS
Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.806
SIT82563.1
Methyltransferase domain-containing protein.
     
 0.775
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
      0.655
SIT82632.1
RNA polymerase, sigma 27/28 subunit, RpsK/SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.630
SIT82556.1
Competence protein ComEA.
       0.554
Your Current Organism:
Edaphobacillus lindanitolerans
NCBI taxonomy Id: 550447
Other names: Bacillus sp. MNA4, CCM 7584, DSM 22424, E. lindanitolerans, strain MNA4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.