STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT84756.1Dimeric dUTPase, all-alpha-NTP-PPase (MazG) superfamily. (161 aa)    
Predicted Functional Partners:
SIT69434.1
DNA-directed RNA polymerase subunit beta.
  
     0.728
SIT84768.1
Hypothetical protein.
 
     0.686
SIT66913.1
Site-specific DNA recombinase.
  
     0.607
SIT66626.1
Uncharacterized protein YpbB.
  
     0.531
SIT68773.1
Predicted dithiol-disulfide isomerase, DsbA family.
  
     0.519
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.515
SIT89629.1
CopG family transcriptional regulator / antitoxin EndoAI.
  
     0.507
SIT93230.1
Nucleotidyltransferase-like.
  
     0.507
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.499
SIT66734.1
Riboflavin biosynthesis RibT protein.
  
     0.441
Your Current Organism:
Edaphobacillus lindanitolerans
NCBI taxonomy Id: 550447
Other names: Bacillus sp. MNA4, CCM 7584, DSM 22424, E. lindanitolerans, strain MNA4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.