STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT89633.1mRNA interferase MazF; Toxic component of a type II toxin-antitoxin (TA) system. (116 aa)    
Predicted Functional Partners:
SIT89629.1
CopG family transcriptional regulator / antitoxin EndoAI.
  
 
 0.971
SIT87412.1
Antitoxin MazE.
 
 
 0.875
SIT89639.1
rsbT co-antagonist protein RsbR.
  
    0.520
SIT89643.1
rsbT antagonist protein RsbS.
       0.511
SIT89647.1
Serine/threonine-protein kinase RsbT.
       0.511
SIT89666.1
RNA polymerase, sigma 37 subunit, RpsB/SigB; Belongs to the sigma-70 factor family.
 
   
 0.495
SIT89625.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.492
SIT89652.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
       0.489
SIT87483.1
Transcriptional regulator CtsR; Belongs to the CtsR family.
  
     0.469
rsbW
Serine/threonine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
     0.459
Your Current Organism:
Edaphobacillus lindanitolerans
NCBI taxonomy Id: 550447
Other names: Bacillus sp. MNA4, CCM 7584, DSM 22424, E. lindanitolerans, strain MNA4
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