STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT93340.1Stage II sporulation protein E. (802 aa)    
Predicted Functional Partners:
SIT67803.1
Stage II sporulation protein GA (sporulation sigma-E factor processing peptidase).
  
  
 0.918
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.817
SIT69654.1
Stage II sporulation protein R.
  
   
 0.814
SIT67789.1
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.806
SIT66784.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.803
SIT69449.1
Sporulation transcriptional regulator SpoIIID.
  
   
 0.793
SIT82632.1
RNA polymerase, sigma 27/28 subunit, RpsK/SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.790
SIT66497.1
Stage IV sporulation protein A.
  
   
 0.789
SIT81770.1
Stage III sporulation protein AH.
  
   
 0.779
SIT82903.1
Stage V sporulation protein B.
  
   
 0.778
Your Current Organism:
Edaphobacillus lindanitolerans
NCBI taxonomy Id: 550447
Other names: Bacillus sp. MNA4, CCM 7584, DSM 22424, E. lindanitolerans, strain MNA4
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