| node1 | node2 | node1 annotation | node2 annotation | score |
| Fbal_0096 | Fbal_1243 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | 0.808 |
| Fbal_0096 | Fbal_1436 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR008207: IPR001789: IPR003594: IPR 003661: IPR005467; KEGG: vch:VC1349 sensory box sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: A3GYU7 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phos [...] | 0.611 |
| Fbal_0096 | Fbal_1472 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR007891: IPR000160; KEGG: sse:Ssed_1116 hypothetical protein; PFAM: GGDEF domain containing protein; CHASE3 domain protein; SMART: GGDEF domain containing protein; SPTR: A3LI29 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; CHASE3 domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.783 |
| Fbal_0096 | Fbal_1653 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Response regulator receiver modulated diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR001789; KEGG: vha:VIBHAR_06170 sensory transduction protein kinase; PFAM: EAL domain protein; response regulator receiver; SMART: EAL domain protein; SPTR: A0YEF2 Response regulator; PFAM: EAL domain; Response regulator receiver domain. | 0.806 |
| Fbal_0096 | Fbal_1925 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: gme:Gmet_0840 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3H131 GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.774 |
| Fbal_0096 | Fbal_2010 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase with extracellular sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR001638; KEGG: she:Shewmr4_1897 diguanylate cyclase; PFAM: GGDEF domain containing protein; extracellular solute-binding protein family 3; SMART: GGDEF domain containing protein; extracellular solute-binding protein family 3; SPTR: A2UZK4 Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; diguanylate cyclase [...] | 0.774 |
| Fbal_0096 | Fbal_2234 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR017440; KEGG: saz:Sama_1829 putative diguanylate phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A0Y7D8 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.805 |
| Fbal_0096 | Fbal_2915 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160; KEGG: mms:mma_0597 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A3RNW6 Sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. | 0.808 |
| Fbal_0096 | Fbal_2970 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR013656: IPR013767: IPR003594: IPR 003660: IPR003661: IPR013655: IPR008207: IPR001789: IPR001610:I PR000014: IPR000700: IPR005467; KEGG: slo:Shew_3200 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator recei [...] | 0.685 |
| Fbal_0096 | Fbal_3482 | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160; KEGG: saz:Sama_0449 regulatory protein CsrD; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A2UWD6 Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain. | 0.805 |
| Fbal_1243 | Fbal_0096 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.808 |
| Fbal_1243 | Fbal_1436 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR008207: IPR001789: IPR003594: IPR 003661: IPR005467; KEGG: vch:VC1349 sensory box sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: A3GYU7 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phos [...] | 0.663 |
| Fbal_1243 | Fbal_1472 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR007891: IPR000160; KEGG: sse:Ssed_1116 hypothetical protein; PFAM: GGDEF domain containing protein; CHASE3 domain protein; SMART: GGDEF domain containing protein; SPTR: A3LI29 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; CHASE3 domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.915 |
| Fbal_1243 | Fbal_1925 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: gme:Gmet_0840 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3H131 GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.811 |
| Fbal_1243 | Fbal_2010 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase with extracellular sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR001638; KEGG: she:Shewmr4_1897 diguanylate cyclase; PFAM: GGDEF domain containing protein; extracellular solute-binding protein family 3; SMART: GGDEF domain containing protein; extracellular solute-binding protein family 3; SPTR: A2UZK4 Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; diguanylate cyclase [...] | 0.826 |
| Fbal_1243 | Fbal_2234 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR017440; KEGG: saz:Sama_1829 putative diguanylate phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A0Y7D8 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.439 |
| Fbal_1243 | Fbal_2915 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160; KEGG: mms:mma_0597 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A3RNW6 Sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. | 0.429 |
| Fbal_1243 | Fbal_2970 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR013656: IPR013767: IPR003594: IPR 003660: IPR003661: IPR013655: IPR008207: IPR001789: IPR001610:I PR000014: IPR000700: IPR005467; KEGG: slo:Shew_3200 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator recei [...] | 0.733 |
| Fbal_1243 | Fbal_3482 | Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dar:Daro_2788 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: B9PA52 Predicted protein; PFAM: EAL domain. | Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160; KEGG: saz:Sama_0449 regulatory protein CsrD; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A2UWD6 Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain. | 0.540 |
| Fbal_1436 | Fbal_0096 | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR008207: IPR001789: IPR003594: IPR 003661: IPR005467; KEGG: vch:VC1349 sensory box sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: A3GYU7 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phos [...] | Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: swp:swp_0095 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A3WK31 Signaling protein with membrane-bound sensor domain and GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.611 |