STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fbal_2000COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097: IPR006096: IPR006095; KEGG: saz:Sama_2067 leucine dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; SPTR: A2V1E0 Glu/Leu/Phe/Val dehydrogenase, dimerisation region; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain. (344 aa)    
Predicted Functional Partners:
Fbal_0657
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002489: IPR002932: IPR006982: IPR000583; KEGG: slo:Shew_1032 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; PRIAM: Glutamate synthase (ferredoxin); SPTR: A2V2C5 Ferredoxin-dependent glutamate synthase; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.993
Fbal_2358
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: saz:Sama_1709 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: A2UZF5 Dehydrogenase, E1 component; PFAM: Dehydrogenase E1 component.
  
 
 0.978
Fbal_2357
Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005476: IPR005475; KEGG: hch:HCH_03686 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit beta; PFAM: Transketolase central region; Transketolase domain protein; SPTR: A3JES1 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
 
 0.958
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.932
Fbal_2373
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839: IPR001412; KEGG: sfr:Sfri_1907 aminotransferase AlaT; PFAM: aminotransferase class I and II; SPTR: A2V5E2 Aminotransferase, class I and II; PFAM: Aminotransferase class I and II.
  
 
 0.929
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581: IPR020558: IPR004404; KEGG: slo:Shew_0292 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: A3Q9L6 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 0.922
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.920
Fbal_0057
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR018967: IPR002932: IPR006622; KEGG: vpa:VPA0765 putative glutamate synthetase; PFAM: ferredoxin-dependent glutamate synthase; Iron sulphur domain-containing, CDGSH-type; SMART: zinc finger CDGSH-type domain protein; SPTR: A3UQB8 Glutamate synthase domain protein; PFAM: Iron-binding zinc finger CDGSH type; Conserved region in glutamate synthase.
  
 
 0.840
Fbal_1017
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932; KEGG: hch:HCH_00332 glutamate synthase domain-containing 2; PFAM: ferredoxin-dependent glutamate synthase; SPTR: A0YEB0 Glutamate synthase domain 2; PFAM: Conserved region in glutamate synthase; Belongs to the glutamate synthase family.
  
 
 0.817
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: shw:Sputw3181_1746 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: A2V1G4 Silent information regulator protein Sir2; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.765
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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