STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fbal_2201Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)    
Predicted Functional Partners:
Fbal_2202
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.971
Fbal_0862
Oxaloacetate decarboxylase alpha subunit; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR003379: IPR000089: IPR001882: IPR 005776; KEGG: saz:Sama_1052 oxaloacetate decarboxylase; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; SPTR: A3UZN5 Oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme; TIGRFAM: oxaloacetate decarboxylase alpha subunit.
  
 
 0.943
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.933
Fbal_1852
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: mmw:Mmwyl1_3029 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: A0ZAM6 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
    
 0.926
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.925
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.925
Fbal_1967
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: sbm:Shew185_2128 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: A2V5D4 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
maeA
COGs: COG0281 Malic enzyme; InterPro IPR001891: IPR012302: IPR012301: IPR015884; KEGG: swp:swp_3875 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: B8CQT6 NAD-dependent malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 
 0.920
Fbal_2550
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150: IPR004184: IPR019777: IPR005949; KEGG: vch:VC1866 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: A3H1R9 Formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
    
 0.920
Fbal_3519
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); COGs: COG0281 Malic enzyme; InterPro IPR012302: IPR012301: IPR015884; KEGG: vha:VIBHAR_00051 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: A0Y278 Putative NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
 
 0.920
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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