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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fbal_2785COGs: COG2225 Malate synthase; InterPro IPR011076: IPR019830: IPR006252; KEGG: saz:Sama_2381 malate synthase; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: A2UVA6 Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (545 aa)    
Predicted Functional Partners:
Fbal_2784
COGs: COG2224 Isocitrate lyase; InterPro IPR000918; KEGG: pap:PSPA7_2573 isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: A0Z837 Isocitrate lyase; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase.
 
 0.999
Fbal_2555
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.987
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.970
Fbal_2492
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810: IPR010953; KEGG: shl:Shal_2494 type II citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: A2V1H7 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
 0.968
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 
 0.951
Fbal_3643
Alanine-glyoxylate aminotransferase apoenzyme; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192: IPR020578; KEGG: saz:Sama_3277 serine--pyruvate transaminase; PFAM: aminotransferase class V; PRIAM: Serine--pyruvate transaminase; SPTR: A3UZX5 Aminotransferase, class V; PFAM: Aminotransferase class-V.
 
 
 0.936
Fbal_1018
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: spc:Sputcn32_1397 acetyl-CoA acetyltransferase; PFAM: Thiolase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: A2V1N9 Acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.935
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.935
Fbal_1767
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.933
maeA
COGs: COG0281 Malic enzyme; InterPro IPR001891: IPR012302: IPR012301: IPR015884; KEGG: swp:swp_3875 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: B8CQT6 NAD-dependent malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
    
 0.923
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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