STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Fbal_3205Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (799 aa)    
Predicted Functional Partners:
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.993
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.986
Fbal_0315
Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001460: IPR001264: IPR011816; KEGG: swd:Swoo_0334 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A2V3F9 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus aga [...]
 
 
0.955
Fbal_0815
Penicillin-binding protein 6; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR018044: IPR001967: IPR012907; KEGG: shl:Shal_3238 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Beta-lactamase; SPTR: A2UY94 Peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family.
  
 
 0.937
Fbal_1929
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D-al anine-endopeptidase; COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: spe:Spro_0479 D-alanyl-D-alanine carboxypeptidase/endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: P45161 D-alanyl-D-alanine carboxypeptidase dacB; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 [...]
     
 0.930
Fbal_3523
Sporulation domain protein; COGs: COG3087 Cell division protein; InterPro IPR007730; KEGG: saz:Sama_0442 sporulation related; PFAM: Sporulation domain protein; SPTR: A3WKL1 Cell division protein, FtsN; PFAM: Sporulation related domain; TIGRFAM: cell division protein FtsN.
 
 
 
 0.916
Fbal_3391
Membrane lipoprotein lipid attachment site; COGs: COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family); InterPro IPR014094; KEGG: sse:Ssed_0914 hypothetical protein; SPTR: A2UZP3 Putative uncharacterized protein; TIGRFAM: membrane lipoprotein lipid attachment site; TIGRFAM: uncharacterized proteobacterial lipoprotein.
    
 
 0.793
Fbal_3206
ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterPro IPR007502: IPR011545: IPR001650: IPR013689: IPR 014001: IPR014021: IPR002464: IPR010225; KEGG: saz:Sama_2972 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A2UWN7 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-te [...]
       0.789
mrdB
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
 
 
 0.748
ftsW
Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 
 
 0.746
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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