| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fbal_0307 | Fbal_3207 | Fbal_0307 | Fbal_3207 | Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453: IPR008136: IPR008135; KEGG: swd:Swoo_0325 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: B1KNC9 CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum [...] | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.476 |
| Fbal_0500 | Fbal_3207 | Fbal_0500 | Fbal_3207 | KEGG: mmb:Mmol_1131 hypothetical protein. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.529 |
| Fbal_0520 | Fbal_0617 | Fbal_0520 | Fbal_0617 | Protein of unknown function DUF2065; InterPro IPR019201; KEGG: swd:Swoo_4220 hypothetical protein; PFAM: Protein of unknown function DUF2065; SPTR: A2V287 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2065). | Protein of unknown function DUF903; InterPro IPR010305; KEGG: vha:VIBHAR_05819 hypothetical protein; PFAM: protein of unknown function DUF903; SPTR: P65297 Uncharacterized lipoprotein ygdR; PFAM: Bacterial protein of unknown function (DUF903). | 0.584 |
| Fbal_0520 | Fbal_3207 | Fbal_0520 | Fbal_3207 | Protein of unknown function DUF2065; InterPro IPR019201; KEGG: swd:Swoo_4220 hypothetical protein; PFAM: Protein of unknown function DUF2065; SPTR: A2V287 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2065). | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.423 |
| Fbal_0617 | Fbal_0520 | Fbal_0617 | Fbal_0520 | Protein of unknown function DUF903; InterPro IPR010305; KEGG: vha:VIBHAR_05819 hypothetical protein; PFAM: protein of unknown function DUF903; SPTR: P65297 Uncharacterized lipoprotein ygdR; PFAM: Bacterial protein of unknown function (DUF903). | Protein of unknown function DUF2065; InterPro IPR019201; KEGG: swd:Swoo_4220 hypothetical protein; PFAM: Protein of unknown function DUF2065; SPTR: A2V287 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2065). | 0.584 |
| Fbal_0617 | Fbal_3207 | Fbal_0617 | Fbal_3207 | Protein of unknown function DUF903; InterPro IPR010305; KEGG: vha:VIBHAR_05819 hypothetical protein; PFAM: protein of unknown function DUF903; SPTR: P65297 Uncharacterized lipoprotein ygdR; PFAM: Bacterial protein of unknown function (DUF903). | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.411 |
| Fbal_2823 | Fbal_3207 | Fbal_2823 | Fbal_3207 | Invasion gene expression up-regulator SirB; COGs: COG3094 conserved hypothetical protein; InterPro IPR007360; KEGG: sse:Ssed_3453 invasion gene expression up-regulator, SirB; PFAM: Invasion gene expression up-regulator SirB; SPTR: A2UWS3 Invasion gene expression up-regulator, SirB; PFAM: Invasion gene expression up-regulator, SirB. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.411 |
| Fbal_3205 | Fbal_3206 | Fbal_3205 | Fbal_3206 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterPro IPR007502: IPR011545: IPR001650: IPR013689: IPR 014001: IPR014021: IPR002464: IPR010225; KEGG: saz:Sama_2972 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A2UWN7 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-te [...] | 0.754 |
| Fbal_3205 | Fbal_3207 | Fbal_3205 | Fbal_3207 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.576 |
| Fbal_3206 | Fbal_3205 | Fbal_3206 | Fbal_3205 | ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterPro IPR007502: IPR011545: IPR001650: IPR013689: IPR 014001: IPR014021: IPR002464: IPR010225; KEGG: saz:Sama_2972 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A2UWN7 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-te [...] | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.754 |
| Fbal_3206 | Fbal_3207 | Fbal_3206 | Fbal_3207 | ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterPro IPR007502: IPR011545: IPR001650: IPR013689: IPR 014001: IPR014021: IPR002464: IPR010225; KEGG: saz:Sama_2972 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A2UWN7 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-te [...] | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.589 |
| Fbal_3207 | Fbal_0307 | Fbal_3207 | Fbal_0307 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453: IPR008136: IPR008135; KEGG: swd:Swoo_0325 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: B1KNC9 CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum [...] | 0.476 |
| Fbal_3207 | Fbal_0500 | Fbal_3207 | Fbal_0500 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | KEGG: mmb:Mmol_1131 hypothetical protein. | 0.529 |
| Fbal_3207 | Fbal_0520 | Fbal_3207 | Fbal_0520 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Protein of unknown function DUF2065; InterPro IPR019201; KEGG: swd:Swoo_4220 hypothetical protein; PFAM: Protein of unknown function DUF2065; SPTR: A2V287 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2065). | 0.423 |
| Fbal_3207 | Fbal_0617 | Fbal_3207 | Fbal_0617 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Protein of unknown function DUF903; InterPro IPR010305; KEGG: vha:VIBHAR_05819 hypothetical protein; PFAM: protein of unknown function DUF903; SPTR: P65297 Uncharacterized lipoprotein ygdR; PFAM: Bacterial protein of unknown function (DUF903). | 0.411 |
| Fbal_3207 | Fbal_2823 | Fbal_3207 | Fbal_2823 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Invasion gene expression up-regulator SirB; COGs: COG3094 conserved hypothetical protein; InterPro IPR007360; KEGG: sse:Ssed_3453 invasion gene expression up-regulator, SirB; PFAM: Invasion gene expression up-regulator SirB; SPTR: A2UWS3 Invasion gene expression up-regulator, SirB; PFAM: Invasion gene expression up-regulator, SirB. | 0.411 |
| Fbal_3207 | Fbal_3205 | Fbal_3207 | Fbal_3205 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.576 |
| Fbal_3207 | Fbal_3206 | Fbal_3207 | Fbal_3206 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterPro IPR007502: IPR011545: IPR001650: IPR013689: IPR 014001: IPR014021: IPR002464: IPR010225; KEGG: saz:Sama_2972 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A2UWN7 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-te [...] | 0.589 |
| Fbal_3207 | bioD | Fbal_3207 | Fbal_1377 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.554 |
| Fbal_3207 | nudJ | Fbal_3207 | Fbal_1993 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | NUDIX hydrolase; InterPro IPR020476: IPR000086: IPR020084; KEGG: swd:Swoo_2704 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: Q3Z2Y5 Phosphatase nudJ; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.466 |