Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Fbal_3401Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001808: IPR000595: IPR018488: IPR018335: IPR 012318; KEGG: swd:Swoo_0662 cAMP-regulatory protein; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: A2UWN4 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (211 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.894
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.869
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.831
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.831
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.821
Fbal_0712
Putative adenylate/guanylate cyclase; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: slo:Shew_1036 putative adenylate/guanylate cyclase; SPTR: A2V2C9 Putative adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
  
 
 0.783
Fbal_3692
COGs: COG3072 Adenylate cyclase; InterPro IPR000274; KEGG: shw:Sputw3181_3725 adenylate cyclase; PFAM: adenylate cyclase class-I; PRIAM: Adenylate cyclase; SPTR: A2UYN9 Adenylate cyclase, class-I; PFAM: Adenylate cyclase, class-I.
  
   
 0.759
Fbal_3017
Putative endonuclease, Z1 domain protein; InterPro IPR018310: IPR005479; KEGG: sfu:Sfum_1320 hypothetical protein; PFAM: Putative endonuclease, Z1 domain; SPTR: A3TJJ6 Endonuclease; PFAM: Z1 domain.
    
 0.731
cpdA
Calcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
   
 0.720
Fbal_3386
COGs: COG3112 conserved hypothetical protein; InterPro IPR008249; KEGG: saz:Sama_0645 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: A1S397 UPF0231 protein Sama_0645; PFAM: Uncharacterised protein family (UPF0231); Belongs to the UPF0231 family.
    
   0.708
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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