| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fbal_0567 | Fbal_2101 | Fbal_0567 | Fbal_2101 | InterPro IPR000866: IPR013740; KEGG: vha:VIBHAR_06328 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; SPTR: A3SX47 Thioredoxin peroxidase; PFAM: AhpC/TSA family. | Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198: IPR013968; KEGG: pin:Ping_2106 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; SPTR: A3UPP7 Probable oxidoreductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.548 |
| Fbal_0567 | Fbal_3573 | Fbal_0567 | Fbal_3573 | InterPro IPR000866: IPR013740; KEGG: vha:VIBHAR_06328 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; SPTR: A3SX47 Thioredoxin peroxidase; PFAM: AhpC/TSA family. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.423 |
| Fbal_1272 | Fbal_3573 | Fbal_1272 | Fbal_3573 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dvl:Dvul_0250 nitroreductase; PFAM: nitroreductase; SPTR: O34475 Putative NAD(P)H nitroreductase yfkO; PFAM: Nitroreductase family. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.408 |
| Fbal_1534 | Fbal_1771 | Fbal_1534 | Fbal_1771 | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR013096: IPR003313: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; PFAM: AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: AraC-like ligand binding domain. | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain. | 0.474 |
| Fbal_1534 | Fbal_3573 | Fbal_1534 | Fbal_3573 | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR013096: IPR003313: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; PFAM: AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: AraC-like ligand binding domain. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.424 |
| Fbal_1771 | Fbal_1534 | Fbal_1771 | Fbal_1534 | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain. | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR013096: IPR003313: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; PFAM: AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: AraC-like ligand binding domain. | 0.474 |
| Fbal_1771 | Fbal_3573 | Fbal_1771 | Fbal_3573 | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.407 |
| Fbal_2101 | Fbal_0567 | Fbal_2101 | Fbal_0567 | Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198: IPR013968; KEGG: pin:Ping_2106 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; SPTR: A3UPP7 Probable oxidoreductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | InterPro IPR000866: IPR013740; KEGG: vha:VIBHAR_06328 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; SPTR: A3SX47 Thioredoxin peroxidase; PFAM: AhpC/TSA family. | 0.548 |
| Fbal_2101 | Fbal_3573 | Fbal_2101 | Fbal_3573 | Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198: IPR013968; KEGG: pin:Ping_2106 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; SPTR: A3UPP7 Probable oxidoreductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.497 |
| Fbal_3573 | Fbal_0567 | Fbal_3573 | Fbal_0567 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | InterPro IPR000866: IPR013740; KEGG: vha:VIBHAR_06328 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; SPTR: A3SX47 Thioredoxin peroxidase; PFAM: AhpC/TSA family. | 0.423 |
| Fbal_3573 | Fbal_1272 | Fbal_3573 | Fbal_1272 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dvl:Dvul_0250 nitroreductase; PFAM: nitroreductase; SPTR: O34475 Putative NAD(P)H nitroreductase yfkO; PFAM: Nitroreductase family. | 0.408 |
| Fbal_3573 | Fbal_1534 | Fbal_3573 | Fbal_1534 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR013096: IPR003313: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; PFAM: AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: AraC-like ligand binding domain. | 0.424 |
| Fbal_3573 | Fbal_1771 | Fbal_3573 | Fbal_1771 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018060; KEGG: spl:Spea_2769 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: A3UNR5 Putative uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain. | 0.407 |
| Fbal_3573 | Fbal_2101 | Fbal_3573 | Fbal_2101 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198: IPR013968; KEGG: pin:Ping_2106 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; SPTR: A3UPP7 Probable oxidoreductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.497 |
| Fbal_3573 | Fbal_3574 | Fbal_3573 | Fbal_3574 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | Transcriptional antiterminator, Rof; InterPro IPR009778; KEGG: cja:CJA_0248 modulator of Rho-dependent transcription termination (ROF) superfamily; PFAM: Modulator of Rho-dependent transcription termination; SPTR: A3UM43 Putative uncharacterized protein; PFAM: Modulator of Rho-dependent transcription termination (ROF). | 0.465 |
| Fbal_3573 | polA | Fbal_3573 | Fbal_3739 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.477 |
| Fbal_3573 | ubiA | Fbal_3573 | Fbal_3575 | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.445 |
| Fbal_3574 | Fbal_3573 | Fbal_3574 | Fbal_3573 | Transcriptional antiterminator, Rof; InterPro IPR009778; KEGG: cja:CJA_0248 modulator of Rho-dependent transcription termination (ROF) superfamily; PFAM: Modulator of Rho-dependent transcription termination; SPTR: A3UM43 Putative uncharacterized protein; PFAM: Modulator of Rho-dependent transcription termination (ROF). | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.465 |
| Fbal_3574 | ubiA | Fbal_3574 | Fbal_3575 | Transcriptional antiterminator, Rof; InterPro IPR009778; KEGG: cja:CJA_0248 modulator of Rho-dependent transcription termination (ROF) superfamily; PFAM: Modulator of Rho-dependent transcription termination; SPTR: A3UM43 Putative uncharacterized protein; PFAM: Modulator of Rho-dependent transcription termination (ROF). | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.618 |
| polA | Fbal_3573 | Fbal_3739 | Fbal_3573 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: vsp:VS_II0102 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A3USF4 Lipoprotein; PFAM: Antibiotic biosynthesis monooxygenase. | 0.477 |