node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aazo_1661 | Aazo_2809 | Aazo_1661 | Aazo_2809 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | 0.934 |
Aazo_1661 | Aazo_3400 | Aazo_1661 | Aazo_3400 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.886 |
Aazo_1661 | Aazo_3612 | Aazo_1661 | Aazo_3612 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: npu:Npun_F4770 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. | 0.918 |
Aazo_1661 | Aazo_3782 | Aazo_1661 | Aazo_3782 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: ava:Ava_2508 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.886 |
Aazo_1661 | Aazo_4841 | Aazo_1661 | Aazo_4841 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: npu:Npun_R2750 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | 0.923 |
Aazo_1661 | ahcY | Aazo_1661 | Aazo_0847 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.946 |
Aazo_1661 | asd | Aazo_1661 | Aazo_2919 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.476 |
Aazo_2808 | Aazo_2809 | Aazo_2808 | Aazo_2809 | KEGG: ana:all2624 hypothetical protein. | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | 0.697 |
Aazo_2809 | Aazo_1661 | Aazo_2809 | Aazo_1661 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
Aazo_2809 | Aazo_2808 | Aazo_2809 | Aazo_2808 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | KEGG: ana:all2624 hypothetical protein. | 0.697 |
Aazo_2809 | Aazo_3400 | Aazo_2809 | Aazo_3400 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.803 |
Aazo_2809 | Aazo_3612 | Aazo_2809 | Aazo_3612 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: npu:Npun_F4770 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. | 0.978 |
Aazo_2809 | Aazo_3782 | Aazo_2809 | Aazo_3782 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | KEGG: ava:Ava_2508 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.803 |
Aazo_2809 | Aazo_4841 | Aazo_2809 | Aazo_4841 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | KEGG: npu:Npun_R2750 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | 0.900 |
Aazo_2809 | ahcY | Aazo_2809 | Aazo_0847 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
Aazo_2809 | asd | Aazo_2809 | Aazo_2919 | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.911 |
Aazo_3400 | Aazo_1661 | Aazo_3400 | Aazo_1661 | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.886 |
Aazo_3400 | Aazo_2809 | Aazo_3400 | Aazo_2809 | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: protein of unknown function DUF39; KEGG: ava:Ava_0664 hypothetical protein. | 0.803 |
Aazo_3400 | Aazo_3612 | Aazo_3400 | Aazo_3612 | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: npu:Npun_F4770 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. | 0.802 |
Aazo_3400 | Aazo_3782 | Aazo_3400 | Aazo_3782 | KEGG: ava:Ava_0452 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: ava:Ava_2508 cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.901 |