STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aazo_3791PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ava:Ava_2504 putative 6-pyruvoyl tetrahydropterin synthase. (421 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.975
folE
TIGRFAM: GTP cyclohydrolase I; KEGG: ava:Ava_2537 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
 
 0.972
Aazo_4074
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ava:Ava_1455 putative 6-pyruvoyl tetrahydropterin synthase.
  
  
  0.927
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.792
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.715
Aazo_0207
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.705
Aazo_3792
PFAM: NurA domain; KEGG: npu:Npun_R5255 hypothetical protein.
       0.506
Aazo_2026
PFAM: YCII-related; KEGG: npu:Npun_F1088 YCII-related.
  
     0.478
hisI
phosphoribosyl-ATP diphosphatase; KEGG: npu:Npun_F4098 phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.469
Aazo_4424
KEGG: npu:Npun_R1700 hypothetical protein.
  
     0.451
Your Current Organism:
Nostoc azollae
NCBI taxonomy Id: 551115
Other names: '. azollae' 0708, 'Nostoc azollae' 0708, Anabaena azollae 0708
Server load: low (14%) [HD]