STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSPOR_11764Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (320 aa)    
Predicted Functional Partners:
FSPOR_9542
Replication fork protection complex subunit tof1/swi1.
   
 0.996
FSPOR_10152
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.989
FSPOR_9348
DNA helicase; Belongs to the MCM family.
   
 
 0.985
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.983
FSPOR_490
Chromosome transmission fidelity 4.
   
 
 0.983
FSPOR_10131
DNA helicase; Belongs to the MCM family.
   
 
 0.979
FSPOR_883
Cell division control 45.
   
 
 0.967
FSPOR_7856
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 
 0.966
FSPOR_9889
DNA helicase; Belongs to the MCM family.
   
 
 0.962
FSPOR_11548
DNA replication complex gins protein psf1.
   
 
 0.961
Your Current Organism:
Fusarium sporotrichioides
NCBI taxonomy Id: 5514
Other names: F. sporotrichioides, Fusarium sporotrichiella var. sporotrichioides
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.