STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSPOR_3935DNA polymerase iv. (816 aa)    
Predicted Functional Partners:
FSPOR_4253
Bifunctional polynucleotide phosphatase kinase.
    
 0.899
FSPOR_7988
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
     
0.897
FSPOR_8817
DNA ligase.
  
 0.884
FSPOR_3548
ATP-dependent dna helicase ii subunit 1.
    
 0.860
FSPOR_5415
DNA ligase.
  
 0.846
FSPOR_3734
DNA ligase.
  
 0.846
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.844
FSPOR_6425
Poly [ADP-ribose] polymerase.
    
 0.830
FSPOR_8458
DNA ligase 4.
  
 0.821
FSPOR_7285
Ap endonuclease 2.
    
 0.814
Your Current Organism:
Fusarium sporotrichioides
NCBI taxonomy Id: 5514
Other names: F. sporotrichioides, Fusarium sporotrichiella var. sporotrichioides
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