STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUMW_137010ENTH domain-containing protein. (400 aa)    
Predicted Functional Partners:
CUMW_225470
AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.
   
 0.728
CUMW_052030
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.719
CUMW_242790
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.710
CUMW_026850
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.638
CUMW_070690
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.619
CUMW_117970
Uncharacterized protein.
    
 0.608
CUMW_194310
Uncharacterized protein.
    
 0.608
CUMW_050080
Uncharacterized protein.
   
 0.595
CUMW_115200
ENTH domain-containing protein.
   
 0.593
CUMW_140890
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 
  0.587
Your Current Organism:
Citrus unshiu
NCBI taxonomy Id: 55188
Other names: C. unshiu, Citrus unshiu Marcow., Satsuma orange, satsuma mandarin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.