STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (447 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 0.997
SDI55007.1
Kynurenine formamidase.
 
  
  0.872
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
     0.781
paaE
ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.
  
  
 0.677
SDI77310.1
Tryptophan 2,3-dioxygenase apoenzyme.
 
 
 0.646
mvaS
hydroxymethylglutaryl-CoA synthase.
   
  
 0.594
SDK00433.1
Beta-carotene 3-hydroxylase.
   
 0.594
SDI76697.1
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily.
   
 0.579
mvaA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
   
  
 0.564
SDJ79509.1
NMT1/THI5 like.
  
     0.537
Your Current Organism:
Flavobacterium glycines
NCBI taxonomy Id: 551990
Other names: F. glycines, Flavobacterium glycines Madhaiyan et al. 2010, Flavobacterium sp. Gm-149, ICMP 17618, NBRC 105008, strain Gm-149
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