| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acs | SDG30228.1 | SAMN05192573_108229 | SAMN05192573_10329 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.941 |
| Acs | SDG30916.1 | SAMN05192573_108229 | SAMN05192573_10348 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.912 |
| Acs | SDH01236.1 | SAMN05192573_108229 | SAMN05192573_10683 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.940 |
| Acs | SDH50819.1 | SAMN05192573_108229 | SAMN05192573_11080 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.912 |
| Acs | SDI04592.1 | SAMN05192573_108229 | SAMN05192573_115117 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase (NAD+). | 0.940 |
| Acs | SDI34994.1 | SAMN05192573_108229 | SAMN05192573_11953 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Allosteric NADP-dependent malic enzyme. | 0.593 |
| Acs | ackA | SAMN05192573_108229 | SAMN05192573_10330 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.927 |
| SDG30201.1 | SDG30228.1 | SAMN05192573_10328 | SAMN05192573_10329 | Hypothetical protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.671 |
| SDG30201.1 | ackA | SAMN05192573_10328 | SAMN05192573_10330 | Hypothetical protein. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.666 |
| SDG30228.1 | Acs | SAMN05192573_10329 | SAMN05192573_108229 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.941 |
| SDG30228.1 | SDG30201.1 | SAMN05192573_10329 | SAMN05192573_10328 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Hypothetical protein. | 0.671 |
| SDG30228.1 | SDG41796.1 | SAMN05192573_10329 | SAMN05192573_103348 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Xylulose-5-phosphate/fructose-6-phosphate phosphoketolase. | 0.952 |
| SDG30228.1 | SDI04592.1 | SAMN05192573_10329 | SAMN05192573_115117 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Aldehyde dehydrogenase (NAD+). | 0.852 |
| SDG30228.1 | SDI34994.1 | SAMN05192573_10329 | SAMN05192573_11953 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Allosteric NADP-dependent malic enzyme. | 0.541 |
| SDG30228.1 | ackA | SAMN05192573_10329 | SAMN05192573_10330 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.999 |
| SDG30916.1 | Acs | SAMN05192573_10348 | SAMN05192573_108229 | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.912 |
| SDG30916.1 | SDH01236.1 | SAMN05192573_10348 | SAMN05192573_10683 | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.909 |
| SDG30916.1 | SDH50819.1 | SAMN05192573_10348 | SAMN05192573_11080 | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.901 |
| SDG30916.1 | SDI04592.1 | SAMN05192573_10348 | SAMN05192573_115117 | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | Aldehyde dehydrogenase (NAD+). | 0.909 |
| SDG30916.1 | SDI34994.1 | SAMN05192573_10348 | SAMN05192573_11953 | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | Allosteric NADP-dependent malic enzyme. | 0.944 |