node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG68582.1 | clpP | SAMN05192573_104343 | SAMN05192573_109161 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.850 |
SDG68582.1 | groL | SAMN05192573_104343 | SAMN05192573_11238 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.625 |
SDG68582.1 | groS | SAMN05192573_104343 | SAMN05192573_11239 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.647 |
SDG68582.1 | grpE | SAMN05192573_104343 | SAMN05192573_101146 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.851 |
SDH41563.1 | SDH41623.1 | SAMN05192573_109162 | SAMN05192573_109163 | Hypothetical protein. | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family. | 0.841 |
SDH41563.1 | clpP | SAMN05192573_109162 | SAMN05192573_109161 | Hypothetical protein. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.774 |
SDH41623.1 | SDH41563.1 | SAMN05192573_109163 | SAMN05192573_109162 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family. | Hypothetical protein. | 0.841 |
SDH41623.1 | clpP | SAMN05192573_109163 | SAMN05192573_109161 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.782 |
SDH92838.1 | clpP | SAMN05192573_11433 | SAMN05192573_109161 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.833 |
SDH92838.1 | groL | SAMN05192573_11433 | SAMN05192573_11238 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
SDH92838.1 | groS | SAMN05192573_11433 | SAMN05192573_11239 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.637 |
SDH92838.1 | grpE | SAMN05192573_11433 | SAMN05192573_101146 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.829 |
clpB | clpP | SAMN05192573_103431 | SAMN05192573_109161 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.834 |
clpB | groL | SAMN05192573_103431 | SAMN05192573_11238 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.648 |
clpB | groS | SAMN05192573_103431 | SAMN05192573_11239 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.589 |
clpB | grpE | SAMN05192573_103431 | SAMN05192573_101146 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.829 |
clpP | SDG68582.1 | SAMN05192573_109161 | SAMN05192573_104343 | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.850 |
clpP | SDH41563.1 | SAMN05192573_109161 | SAMN05192573_109162 | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Hypothetical protein. | 0.774 |
clpP | SDH41623.1 | SAMN05192573_109161 | SAMN05192573_109163 | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family. | 0.782 |
clpP | SDH92838.1 | SAMN05192573_109161 | SAMN05192573_11433 | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.833 |