| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KFX03043.1 | KFX07157.1 | KP22_16665 | KP22_03440 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| KFX03043.1 | glyA | KP22_16665 | KP22_18170 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.841 |
| KFX03043.1 | gshA | KP22_16665 | KP22_17010 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.734 |
| KFX03043.1 | gshB | KP22_16665 | KP22_10595 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. | 0.744 |
| KFX03043.1 | pepA | KP22_16665 | KP22_14315 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.765 |
| KFX03043.1 | pepB | KP22_16665 | KP22_18080 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminopeptidase B; Probably plays an important role in intracellular peptide degradation. | 0.742 |
| KFX03043.1 | pepN | KP22_16665 | KP22_03460 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| KFX03043.1 | secD | KP22_16665 | KP22_00135 | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.413 |
| KFX07157.1 | KFX03043.1 | KP22_03440 | KP22_16665 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| KFX07157.1 | gshA | KP22_03440 | KP22_17010 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate--cysteine ligase; Involved in the first step of glutathione biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.708 |
| KFX07157.1 | pepA | KP22_03440 | KP22_14315 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.734 |
| KFX07157.1 | pepB | KP22_03440 | KP22_18080 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminopeptidase B; Probably plays an important role in intracellular peptide degradation. | 0.734 |
| KFX07157.1 | pepN | KP22_03440 | KP22_03460 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.794 |
| KFX07157.1 | sseA | KP22_03440 | KP22_18065 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.731 |
| KFX07219.1 | pepA | KP22_03770 | KP22_14315 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.460 |
| KFX07219.1 | pepB | KP22_03770 | KP22_18080 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Aminopeptidase B; Probably plays an important role in intracellular peptide degradation. | 0.460 |
| KFX07219.1 | pepN | KP22_03770 | KP22_03460 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.780 |
| KFX07219.1 | secD | KP22_03770 | KP22_00135 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.743 |
| glyA | KFX03043.1 | KP22_18170 | KP22_16665 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminoacyl-histidine dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.841 |
| glyA | gshB | KP22_18170 | KP22_10595 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. | 0.707 |
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