node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KFX03754.1 | lpxM | KP22_14920 | KP22_03655 | Catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.716 |
KFX03754.1 | lpxT | KP22_14920 | KP22_02735 | Catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. | 0.806 |
KFX03754.1 | pagP | KP22_14920 | KP22_17650 | Catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A palmitoyltransferase; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. | 0.778 |
KFX06091.1 | KFX07158.1 | KP22_09575 | KP22_03445 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
KFX06091.1 | KFX07197.1 | KP22_09575 | KP22_03650 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.681 |
KFX06091.1 | lpxM | KP22_09575 | KP22_03655 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.695 |
KFX07158.1 | KFX06091.1 | KP22_03445 | KP22_09575 | Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.772 |
KFX07158.1 | KFX07197.1 | KP22_03445 | KP22_03650 | Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.782 |
KFX07158.1 | lpxM | KP22_03445 | KP22_03655 | Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.707 |
KFX07197.1 | KFX06091.1 | KP22_03650 | KP22_09575 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.681 |
KFX07197.1 | KFX07158.1 | KP22_03650 | KP22_03445 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porin; Allows for ions and hydrophilic solutes to cross the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.782 |
KFX07197.1 | lpxM | KP22_03650 | KP22_03655 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.705 |
lpxB | lpxK | KP22_08010 | KP22_03370 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.974 |
lpxB | lpxL | KP22_08010 | KP22_07305 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.703 |
lpxB | lpxM | KP22_08010 | KP22_03655 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.750 |
lpxB | lpxP | KP22_08010 | KP22_09310 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A biosynthesis palmitoleoyl acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. | 0.747 |
lpxK | lpxB | KP22_03370 | KP22_08010 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.974 |
lpxK | lpxL | KP22_03370 | KP22_07305 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.571 |
lpxK | lpxM | KP22_03370 | KP22_03655 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.696 |
lpxK | lpxP | KP22_03370 | KP22_09310 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipid A biosynthesis palmitoleoyl acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. | 0.651 |