STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (274 aa)    
Predicted Functional Partners:
KFX06073.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.932
KFX03480.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.849
KFX05441.1
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.847
KFX04387.1
Spore coat protein CotH; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.808
KFX03319.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.804
KFX06074.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
       0.797
cpdA-2
Diguanylate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 
0.782
KFX07510.1
Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.777
KFX02896.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.768
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.768
Your Current Organism:
Pectobacterium betavasculorum
NCBI taxonomy Id: 55207
Other names: ATCC 43762, CFBP 2122, CIP 105193, DSM 18076, Erwinia carotovora subsp. betavasculorum, ICMP 4226, LMG 2464, LMG 2466, LMG:2464, LMG:2466, NCPPB 2795, P. betavasculorum, Pectobacterium carotovorum subsp. betavasculorum, UCPB 193
Server load: medium (62%) [HD]