node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KFX00585.1 | KFX00586.1 | KP22_19880 | KP22_19885 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KFX00585.1 | KFX05291.1 | KP22_19880 | KP22_11325 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
KFX00585.1 | KFX05965.1 | KP22_19880 | KP22_08895 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
KFX00585.1 | KFX06001.1 | KP22_19880 | KP22_09090 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
KFX00585.1 | KFX06735.1 | KP22_19880 | KP22_01195 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
KFX00585.1 | aceE | KP22_19880 | KP22_11315 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.748 |
KFX00585.1 | aceF | KP22_19880 | KP22_11320 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.983 |
KFX00585.1 | sthA | KP22_19880 | KP22_19655 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.956 |
KFX00585.1 | sucC | KP22_19880 | KP22_01205 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.526 |
KFX00585.1 | sucD | KP22_19880 | KP22_01210 | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.425 |
KFX00586.1 | KFX00585.1 | KP22_19885 | KP22_19880 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KFX00586.1 | KFX05291.1 | KP22_19885 | KP22_11325 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
KFX00586.1 | KFX05965.1 | KP22_19885 | KP22_08895 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
KFX00586.1 | KFX06001.1 | KP22_19885 | KP22_09090 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
KFX00586.1 | KFX06735.1 | KP22_19885 | KP22_01195 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
KFX00586.1 | aceE | KP22_19885 | KP22_11315 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.768 |
KFX00586.1 | aceF | KP22_19885 | KP22_11320 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.950 |
KFX00586.1 | sthA | KP22_19885 | KP22_19655 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.882 |
KFX05291.1 | KFX00585.1 | KP22_11325 | KP22_19880 | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
KFX05291.1 | KFX00586.1 | KP22_11325 | KP22_19885 | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |