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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlTranscriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (124 aa)    
Predicted Functional Partners:
frsA
Fermentation/respiration switch protein; Forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0255 family.
 
     0.819
KFX05412.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
viaA
Hypothetical protein; Contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
zapC
Cell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.753
KFX07438.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.750
KFX07859.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0227 family.
  
     0.734
KFX01481.1
ATP synthase F0F1 subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.728
KFX05821.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0325 family.
  
     0.725
KFX00664.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
ilvM
Acetolactate synthase 2 regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.718
Your Current Organism:
Pectobacterium betavasculorum
NCBI taxonomy Id: 55207
Other names: ATCC 43762, CFBP 2122, CIP 105193, DSM 18076, Erwinia carotovora subsp. betavasculorum, ICMP 4226, LMG 2464, LMG 2466, LMG:2464, LMG:2466, NCPPB 2795, P. betavasculorum, Pectobacterium carotovorum subsp. betavasculorum, UCPB 193
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