| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HA50_01090 | HA50_20015 | HA50_01090 | HA50_20015 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Murein hydrolase activator EnvC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.977 |
| HA50_01090 | ftsE | HA50_01090 | HA50_01085 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.997 |
| HA50_01090 | ftsY | HA50_01090 | HA50_01080 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.866 |
| HA50_01090 | macB | HA50_01090 | HA50_29630 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Macrolide ABC transporter permease/ATP-binding protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.521 |
| HA50_01090 | rpoH | HA50_01090 | HA50_01095 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.548 |
| HA50_01090 | rsmD | HA50_01090 | HA50_01075 | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.563 |
| HA50_20015 | HA50_01090 | HA50_20015 | HA50_01090 | Murein hydrolase activator EnvC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.977 |
| HA50_20015 | ftsE | HA50_20015 | HA50_01085 | Murein hydrolase activator EnvC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.581 |
| ftsE | HA50_01090 | HA50_01085 | HA50_01090 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.997 |
| ftsE | HA50_20015 | HA50_01085 | HA50_20015 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Murein hydrolase activator EnvC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.581 |
| ftsE | ftsY | HA50_01085 | HA50_01080 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.866 |
| ftsE | ftsZ | HA50_01085 | HA50_03495 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.651 |
| ftsE | guaB | HA50_01085 | HA50_14375 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.821 |
| ftsE | guaC | HA50_01085 | HA50_03535 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.577 |
| ftsE | macB | HA50_01085 | HA50_29630 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Macrolide ABC transporter permease/ATP-binding protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.583 |
| ftsE | rpoH | HA50_01085 | HA50_01095 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.569 |
| ftsE | rsmD | HA50_01085 | HA50_01075 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.575 |
| ftsE | tsaD | HA50_01085 | HA50_17530 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.591 |
| ftsY | HA50_01090 | HA50_01080 | HA50_01090 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.866 |
| ftsY | ftsE | HA50_01080 | HA50_01085 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.866 |