STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HA50_06300Multidrug export protein EmrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)    
Predicted Functional Partners:
macB
Macrolide ABC transporter permease/ATP-binding protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 0.981
HA50_06310
RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.952
HA50_06305
EmrB/QacA family drug resistance transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
     0.946
HA50_13800
EmrB/QacA family drug resistance transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.758
HA50_30040
EmrB/QacA family drug resistance transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
     0.730
emrB
Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
     0.723
HA50_15635
RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.707
HA50_20180
Multidrug RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.688
mdtB
Multidrug transporter subunit MdtB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
  0.661
HA50_15655
RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.641
Your Current Organism:
Pantoea cypripedii
NCBI taxonomy Id: 55209
Other names: ATCC 29267, Bacillus cypripedii, CFBP 3613, CIP 105195, DSM 3873, Erwinia carotovora var. cypripedii, Erwinia cypripedii, Erwinia cyrpipedii, LMG 2655, LMG 2657, LMG:2655, LMG:2657, NCPPB 3004, P. cypripedii, Pectobacterium cypripedii
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