| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HA50_02500 | HA50_11865 | HA50_02500 | HA50_11865 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe2+-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| HA50_02500 | HA50_11870 | HA50_02500 | HA50_11870 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
| HA50_02500 | HA50_16990 | HA50_02500 | HA50_16990 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
| HA50_02500 | HA50_17325 | HA50_02500 | HA50_17325 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | tonB-system energizer ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| HA50_02500 | HA50_28175 | HA50_02500 | HA50_28175 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | arpA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.765 |
| HA50_02500 | entF | HA50_02500 | HA50_02540 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-ribosomal peptide synthetase; With EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| HA50_02500 | tolQ | HA50_02500 | HA50_05670 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.430 |
| HA50_10620 | HA50_11870 | HA50_10620 | HA50_11870 | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.678 |
| HA50_10620 | HA50_17320 | HA50_10620 | HA50_17320 | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | TonB system transport protein ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
| HA50_10620 | HA50_17325 | HA50_10620 | HA50_17325 | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | tonB-system energizer ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.979 |
| HA50_10620 | tolQ | HA50_10620 | HA50_05670 | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.961 |
| HA50_10620 | tolR | HA50_10620 | HA50_05675 | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.973 |
| HA50_11865 | HA50_02500 | HA50_11865 | HA50_02500 | Fe2+-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| HA50_11865 | HA50_11870 | HA50_11865 | HA50_11870 | Fe2+-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| HA50_11870 | HA50_02500 | HA50_11870 | HA50_02500 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
| HA50_11870 | HA50_10620 | HA50_11870 | HA50_10620 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.678 |
| HA50_11870 | HA50_11865 | HA50_11870 | HA50_11865 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe2+-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| HA50_11870 | HA50_16990 | HA50_11870 | HA50_16990 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.840 |
| HA50_11870 | HA50_17320 | HA50_11870 | HA50_17320 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | TonB system transport protein ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.668 |
| HA50_11870 | HA50_17325 | HA50_11870 | HA50_17325 | Catecholate siderophore receptor Fiu; Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tonB-system energizer ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |