| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HA50_08655 | HA50_15505 | HA50_08655 | HA50_15505 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
| HA50_08655 | HA50_22025 | HA50_08655 | HA50_22025 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| HA50_08655 | HA50_22115 | HA50_08655 | HA50_22115 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.732 |
| HA50_08655 | HA50_27895 | HA50_08655 | HA50_27895 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | IscS subfamily cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.732 |
| HA50_08655 | iscS | HA50_08655 | HA50_14465 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.732 |
| HA50_08655 | nfuA | HA50_08655 | HA50_19110 | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.740 |
| HA50_12760 | HA50_22025 | HA50_12760 | HA50_22025 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| HA50_12760 | djlA | HA50_12760 | HA50_03340 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.938 |
| HA50_12760 | nfuA | HA50_12760 | HA50_19110 | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.605 |
| HA50_15505 | HA50_08655 | HA50_15505 | HA50_08655 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.718 |
| HA50_15505 | HA50_22025 | HA50_15505 | HA50_22025 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| HA50_15505 | HA50_22115 | HA50_15505 | HA50_22115 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.742 |
| HA50_15505 | HA50_27895 | HA50_15505 | HA50_27895 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.742 |
| HA50_15505 | iscS | HA50_15505 | HA50_14465 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.742 |
| HA50_15505 | nfuA | HA50_15505 | HA50_19110 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.740 |
| HA50_22025 | HA50_08655 | HA50_22025 | HA50_08655 | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.976 |
| HA50_22025 | HA50_12760 | HA50_22025 | HA50_12760 | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| HA50_22025 | HA50_15505 | HA50_22025 | HA50_15505 | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| HA50_22025 | HA50_22030 | HA50_22025 | HA50_22030 | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrogenase cofactor biosynthesis protein NifB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| HA50_22025 | HA50_22115 | HA50_22025 | HA50_22115 | Nitrogen fixation protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.975 |