STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGJ47431.1Deoxyribonuclease IV. (289 aa)    
Predicted Functional Partners:
EGJ46827.1
Exodeoxyribonuclease III.
    
 0.943
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.840
EGJ47432.1
xaa-Pro aminopeptidase.
  
    0.818
EGJ47430.1
HAD phosphatase, family IIIA.
       0.815
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
    0.630
EGJ47434.2
Hypothetical protein.
 
     0.597
EGJ47429.1
Hypothetical protein.
       0.534
EGJ46342.1
Manganese-dependent inorganic pyrophosphatase.
  
    0.445
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.445
EGJ47815.1
CxxC-x17-CxxC domain-containing protein.
  
     0.432
Your Current Organism:
Ruminococcaceae bacterium D16
NCBI taxonomy Id: 552398
Other names: R. bacterium D16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.