STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGJ46730.1Stage V sporulation protein AC. (146 aa)    
Predicted Functional Partners:
EGJ47017.1
Stage V sporulation protein AD.
 
  
 0.942
EGJ47016.1
Stage V sporulation protein AE.
 
  
 0.863
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.850
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.829
EGJ46725.1
Stage IV sporulation protein B.
 
     0.817
EGJ48085.2
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.808
EGJ46724.2
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
   
 0.802
EGJ47202.2
Sporulation transcriptional regulator SpoIIID.
  
   
 0.789
EGJ45694.1
Hypothetical protein.
  
  
 0.788
EGJ46909.1
Hypothetical protein.
  
    0.785
Your Current Organism:
Ruminococcaceae bacterium D16
NCBI taxonomy Id: 552398
Other names: R. bacterium D16
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