node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEN82412.1 | gcvH | POREN0001_1796 | POREN0001_1070 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.594 |
EEN82412.1 | gcvP | POREN0001_1796 | POREN0001_0751 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. | 0.990 |
EEN82412.1 | gcvT | POREN0001_1796 | POREN0001_0880 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.567 |
EEN82412.1 | gdh | POREN0001_1796 | POREN0001_0509 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Glutamate dehydrogenase, NAD-specific; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.589 |
EEN82412.1 | glyA | POREN0001_1796 | POREN0001_0886 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.971 |
EEN82412.1 | lpdA | POREN0001_1796 | POREN0001_0064 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.505 |
EEN82412.1 | nifJ | POREN0001_1796 | POREN0001_0794 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. | 0.424 |
EEN82412.1 | purD | POREN0001_1796 | POREN0001_0458 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. | 0.999 |
EEN83275.1 | gcvP | POREN0001_1061 | POREN0001_0751 | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. | 0.994 |
EEN83275.1 | glyA | POREN0001_1061 | POREN0001_0886 | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.424 |
EEN83275.1 | lpdA | POREN0001_1061 | POREN0001_0064 | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.415 |
EEN83275.1 | nifJ | POREN0001_1061 | POREN0001_0794 | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. | 0.976 |
gcvH | EEN82412.1 | POREN0001_1070 | POREN0001_1796 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | 0.594 |
gcvH | gcvP | POREN0001_1070 | POREN0001_0751 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | POREN0001_1070 | POREN0001_0880 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH | gdh | POREN0001_1070 | POREN0001_0509 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamate dehydrogenase, NAD-specific; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.815 |
gcvH | glyA | POREN0001_1070 | POREN0001_0886 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
gcvH | lpdA | POREN0001_1070 | POREN0001_0064 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.969 |
gcvP | EEN82412.1 | POREN0001_0751 | POREN0001_1796 | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. | 0.990 |
gcvP | EEN83275.1 | POREN0001_0751 | POREN0001_1061 | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.994 |