STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fklBPeptidyl-prolyl cis-trans isomerase, FKBP-type; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00254; match to protein family HMM PF01346. (198 aa)    
Predicted Functional Partners:
EEN82881.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00183; match to protein family HMM PF02518.
   
 0.877
EEN82986.1
Peptidyl-prolyl cis-trans isomerase, FKBP-type; Identified by match to protein family HMM PF00254.
 
    
0.762
EEN82997.1
Peptidyl-prolyl cis-trans isomerase, FKBP-type; Identified by match to protein family HMM PF00254; match to protein family HMM PF01346.
 
    
0.751
EEN83151.1
Hypothetical protein.
    
   0.719
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.688
lysC
Amino acid kinase family; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
    
   0.591
ppiA
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.550
EEN82739.1
Hypothetical protein.
    
   0.544
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.543
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
  0.501
Your Current Organism:
Porphyromonas endodontalis
NCBI taxonomy Id: 553175
Other names: P. endodontalis ATCC 35406, Porphyromonas endodontalis ATCC 35406, Porphyromonas endodontalis str. ATCC 35406, Porphyromonas endodontalis strain ATCC 35406
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.